Copper Peptides and Skin Regeneration
Biochemical analysis of the snail's fluid substance we collect, shows it contains complex glycoconjugates. They comprise glycosaminoglycans, glycoproteins, proteoglycans, copper peptides, enzymes, co-enzymes and oligoelements (copper, zinc, calcium and iron ).
Copper Peptides
In the snail's body tissues, glycosaminoglycans (GAGs) are primarily located inside granules and in the shell, and are secreted onto the surface as a mucous material. Snail glycosaminoglycans tightly binds divalent copper cations (Cu 2+) and form copper peptides, with reportedly have skin regeneration properties. The concentration of copper in the snail mucins is notable, but copper peptides have been shown to be active in nanomolar amounts.
Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5):H1821-7. http://ajpheart.physiology.org/cgi/content/full/282/5/H1821
Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing.
Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery .
Aging reversal of skin
The greatest interest in copper peptides is in the area of reversing the effects of human ageing and ultraviolet damage on human skin. During ageing, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number.
A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
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Made in the USA. One Month's supply 50 grams = 1.76 oz
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BIOCUTIS skin treatment products
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A deeply moisturizing and naturally invigorating skin cream that stimulates healing of injured cells and skin lesions. Restores the capacity of the skin to remain hydrated. Replenishes the lipid barrier of the skin thereby impeding the penetration of allergens and toxins. Induces the proliferation of antimicrobial peptides on the surface of the skin and within the skin follicles contributing to control microbes that cause folliculitis and acne.
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Prevents abnormal scars and gets rid of scars from accidents, surgery, stretch marks; and abnormal scars such as hypertrophic and keloid scars. Relieves chicken skin. Reduces actinic keratosis lesions. All by breaking down abnormal, dysfunctional and damaged tissues into their amino acid components while stimulating their replacement with new healthy skin structures. Vanishes redness and dryness, relieves eczema and dermatitis, reduces psoriasis scales and most types of skin blemishes.
Repairs skin damaged by glycolic peeling and other chemical peels, dermabrasion or laser resurfacing.
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BIOSKINRELIEF ™
Our product for men and woman who experience skin irritation when shaving or when using other methods of hair removal. It contains the same ingredients in BIOSKINCARE plus Butterbur Extract (Petasites Japonicus Root Extract), a botanical ingredient that relieves itching and irritation. 50 gram (1.76 oz) jar = $69.95 and for two or more 20% off.
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Same cream base and enzymes as in BIOSKINCARE to "digest" or dissolve blemishes, speed skin turnover, moisturize and tighten skin, and two added ingredients: a natural pigment reducer and a human growth factor peptide, derived from the melanocyte-stimulating-hormone that blocks melanin synthesis, and inhibits the formation of unwanted pigmentation, allowing control over skin tone and brown spots. Leaves skin bright and refreshed! 50 gram (1.76 oz) jar = $79.
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A home micro-dermabrasion cream with high quality micro-crystals, the same that professionals use to breakdown and polish away hard, rough and old scar tissues. It allows for a deeper penetration of our all natural skin moisturizing and regeneration complex that is combined with the crystals in the microdermabrasion cream.120 gram (4 oz) jar = $89
BIO STRETCH MARK CREAM™
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An oil free gel for acne, rosacea and facial scars, for people with very oily skin complexion. The product is based on the biological glycoconjugates compound produced to function as a powerful immune modulator and skin regeneration trigger by the snail of the species Helix Aspersa Müller. Removes dead cells and the debris and/or keratin plugs that block sebum canals. And dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the secretion of antimicrobials on the skin surface that keep microbes at bay and control acne bacteria. Boosts the production of glycosaminoglycans, the water holging molecules in healthy skin, thus truly moisturizing the skin from within. Signals the immune system that the body is being taken care of and can moderate an otherwise severe inflammatory reaction that may end in the destruction of healthy skin cells together with bacteria and sebum that has turned into a foreign matter. 50 gram (1.76 oz) airless pump bottle $59 and 20% off for two or more.
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Clears keratosis pilaris and actinic keratosis scales by the action of two ingredients: the enzymes in a biological serum and salicylic acid as is naturally in willow bark extract. As the keratin and damaged cells are broken down into their amino-acid and other components they are used for the regeneration of all the structural components of healthy skin. Product is in a 2oz pump bottle. Price is $60 and you get a 20% discount when you order more than one.
Disclaimer: The information provided at this website and our natural skin care products are not an alternative to the advice of a Doctor or medical practitioner. Please consult your physician if you have a medical condition.
